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Selected Publications

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ARTICLES
Nemecz M, Popov D, Georgescu A.
Phosphorylation/dephosphorylation signaling events in the aorta of streptozotocin-injected Golden Syrian Hamsters. Annals of RSCB, (CNCSIS B+) vol XV, issue 1, 28-34, 2010.

Chahed S, Leroyer AS, Benzerroug M, Gaucher D, Georgescu A, Picaud S, J-S Silvestre, Gaudric A, Tedgui A, Massin P, Boulange CM. Increased vitreous shedding of microparticles in proliferative diabetic retinopathy stimulates endothelial proliferation. Diabetes , 59:694-701, 2010.

Alexandru N, Popov D, Dragan E, Andrei E and Georgescu A. Platelet activation in hypertension associated with hypercholesterolemia; effects of irbesartan. Journal of Thrombosis and Hemostasis, DOI:10.1111/j.1538-7836.2010.04122.x., in press 2010.

Georgescu A, Popov D, Constantin A, Nemecz M, Alexandru N, Cochior D, Tudor A. Dysfunction of human subcutaneous FAT arterioles in obesity associated or not with Type 2 diabetes. Clinical Science, in press 2010.

Simionescu M, Popov D, Sima A. Endothelial transcytosis in health and disease. Cell Tissue Res 335:27-40, 2009.

Popov D. Vascular PTPs: Current developments and challenges for exploitation on Type 2 diabetes-associated vascular dysfunction, Biochem Biophys Res Commun , 389: 1-4, 2009.

Popov D, Nemecz M, Dumitrescu M, Georgescu A, Böhmer F. D. Long-term high glucose concentration influences Akt, ERK1/2, and PTP1B protein expression in human aortic smooth muscle cells, Biochem Biophys Res Commun, 388: 51-55, 2009.

Georgescu A, Alexandru N, Popov D, Amuzescu M, Andrei E, Zamfir C, Maniu H, Badila A. Chronic venous insufficiency is associated with elevated level of circulating microparticles. J. Thrombosis and Haemostasis, 7: 1566-1575, 2009.

Georgescu A, Pluteanu F, Flonta M-L, Badila E, Dorobantu M, Popov D. Nebivolol induces the hyperpolarizing effect on smooth muscle cells in the mouse renal artery by activation of the b2 - adrenoceptor, Pharmacology, 81, 110-117, 2008.

Alexandru N, Jardín I, Popov D, Simionescu M, García-Estañ J, Salido GM, Rosado JA. Effect of homocysteine on calcium concentation and platelet function in type 2 diabetes mellitus. J. Cell. Mol. Med. 12, 2015-2026. 2008.

Alexandru N, Constantin A, Popov D
. Carbonylation of platelet proteins occurs as consequence of oxidative stress and thrombin activation, and is stimulated by ageing and type 2 diabetes. Clin Chem Lab Med, 46(4): 528–536, 2008.


Georgescu A, Popov D, Dragan E, Dragomir E, Badila E. Protective effects of nebivolol and reversal of endothelial dysfunction in diabetes associated with hypertension. Eur. J. Pharmacol., 570, 149-158, 2007.

Popov D, Radu DL. The role of hyperglycemia in the development of diabetic complications investigated in transgenic mouse model, in: "Vascular Involvement in Diabetes: Clinical, Experimental and Beyond", D.M. Cheta, (ed.), Karger and the Publishing House of the Romanian Academy, 2005, pp. 121-134.

Constantin A, Constantinescu E, Dumitrescu M, Calin A, Popov D. Effect of ageing on carbonyl stress and antioxidant defending in RBC of obese Type 2 diabetic patients, J. Cell. Molecular Medicine 9: 683-691, 2005.

Popov D. Towards understanding the mechanisms of impeded vascular function in the diabetic kidney. In: Cellular Dysfunction in Atherosclerosis and Diabetes - Reports from Bench to Bedside, Eds. Maya Simionescu, Anca Sima, Doina Popov, The Publishing House of the Romanian Academy, Bucharest, Romania, 244-259, 2004.

Popov D, Simionescu M, Shepherd PR. Saturated-fat diet induces moderate diabetes and severe glomerulosclerosis in hamsters, Diabetologia 46: 1408-1418, 2003.

Costache G, Popov D, Georgescu A, Cenuse M, Jinga VV, Simionescu M. The effects of simultaneous hyperlipemia-hyperglycemia on the mesenteric resistance arteries, myocardium and kidney glomeruli. J. Submicrosc. Cytol. Pathol., 32, 47-58, 2000.

Schmidt AM, Hasu M, Popov D, Zhang JH, Chen J, Yan SD, Brett J, Cao R, Kuwabara K, Costache G, Simionescu N, Simionescu M, Stern D. Receptor for advanced glycation endproduct (AGEs) has a central role in vessel wall interactions and gene activation in response to circulating proteins. Proc. Nat. Acad. Sci. USA, 91, 8807-8811, 1994.


B
OOKS

Alexandru N. Disfunctia plachetara in imbatranire si patologia cardiovasculara, Editura Agir, Bucuresti,159 pag., ISBN 978-973-720-289-5, 2010.

Georgescu A, Antohe F. Editor of the international monograph ‘From Vascular Cell Biology to Cardiovascular Medicine’ published by RESEARCH SIGNPOST TRANSWORLD RESEARCH NETWORK, Trivandrum - 695023, Kerala, India, ISBN - 978-81-7895-503-2, in press 2010.


CHAPTERS IN BOOKS

Georgescu A, Alexandru N, Popov D. Ongoing data on vascular endothelial cell dysfunction: an update. ‘From Vascular Cell Biology to Cardiovascular Medicine’, Ed: Adriana Georgescu, Felicia Antohe, published by RESEARCH SIGNPOST TRANSWORLD RESEARCH NETWORK, ISBN - 978-81-7895-503-2 , in press 2010.