Laboratories
Lipidomics and Atherosclerosis
| Sraff | Head
Anca V. Sima, Ph.D.
Camelia S. Stancu, Ph.D.
Loredan St. Niculescu, Ph.D.
Laura Toma, Ph.D.
Gabriela M. Botez, Ph.D. student
Cristina Dobre, Technical assistant |
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| Anca V. Sima | 
Anca V. Sima, Ph.D.
Major positions and appointments
- Associate Member of the Romanian Academy
- Ph.D. Advisor in Biology Advisor graduate and master program
- Member of the Scientific Council
- Secretary of the Bucharest Branch of the Romanian Society for Cell Biology
- Executive Director of the Advanced Study Course in Cellular and Molecular Medicine
- Expert grant evaluator at European Community FPs, national and international
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| Current Projects | Effect of irreversibly glycated LDL (AGE-LDL) on human endothelial and vascular smooth muscle cells
An in vitro model was set up to study the effect of modified lipoproteins on human endothelial cells (EC) and smooth muscle cells (SMC): lipid loading, oxidative and inflammatory stress.
Effect of AGE-LDL on endothelial cells
Thus far, we found that exposure of EC to advanced glycation end products modified LDL (AGE-LDL) induce a significant increase of NADPHox activity (40%, p<0.05), RAGE e
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