icbp

Adrian Manea, Ph.D.
Laurentia Tanase, Master student
Anca Violeta Gafencu, Ph. D. – group leader
Madalina Fenyo, Ph. D. student
Irina Florea, Master student
Floarea Georgescu, Technical asistant

The activity of the laboratory is divided in two specialized groups:

1. Cell Pharmacology and Gene Regulation
Monica Raicu – group leader
Adrian Manea
Laurentia Tanase
Floarea Georgescu

MAJOR RESEARCH INTERESTS OF THE GROUP

Cell biology of cardio
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In collaboration with former research staff :
Rozalia Mora, Serban I.Tasca, Nicolae Ghinea, Anton Fixman, Lucian Ghitescu, Stela Florea, Luminita Pojoga

Identification and characterization of albumin binding proteins of capillary endothelium

Work done in our Institute demonstrated that capillary endothelium of murine heart, lung, diaphragm, skeletal muscle and adipose tissue express specific albumin binding proteins (ABP), restricted mainly to plasmalemmal vesicles open to the luminal and ablumin

Molecular mechanisms involved in the regulation of NAD(P)H oxidases in endothelial and smooth muscle cells

1. Role of signaling pathways JAK/STAT, NF-kB and C/EBP
Emerging clinical and experimental evidence demonstrates the role of oxidative stress in the development of cardiovascular disorders. In particular, vascular smooth muscle cells (SMCs) undergo phenotypic switching in response to vascular injury. Reactive oxygen species (ROS) are implicated in a variety of processes involved in vascular
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