Projects
Projects
In progress
Ongoing Projects
| 2023–2026 |
Strengthening Romanian competence in metabolic syndrome research by exploring the role of apolipoprotein A2 in dyslipidemia, obesity, and type II diabetes mellitus STROMA · PNRR project (contract 258/2023) · Led by Kyriakos Kypreos |
| 2023–2026 |
Comprehensive and personalized assessment of acute coronary syndrome by multiomic approach and artificial intelligence strategy CARDIOSCOPE · HORIZON-MSCA-2021-SE-01-01, Grant Agreement nº 101086397 · Project director Dr. Paolo Magni, University of Milan · Coordinator of the Romanian team: Anca Gafencu |
1996–2024
Completed Projects
| 2022–2024 |
“A novel anti-atherosclerotic chimeric protein that impedes the infiltration of the inflammatory cells in the vessel wall” PN-III-P4-PCE-2021-1755 · Project Director A. Gafencu |
| 2020–2022 |
Demonstration of the enhanced anti-atherosclerotic potential of apolipoprotein E targeted to the activated endothelium, by fusion with VCAM-1 binding peptide PN-III-P2-2.1-PED-2019-4574 · Project Director A. Gafencu |
| 2019–2022 |
Integrative Personal Omics Profiles in Glioblastoma Recurrence and Therapy Resistance ERA-NET PerMed · A. Gafencu, Coordinator for the Romanian team |
| 2016–2020 |
Improve institutional competitiveness in the field of type 1 diabetes by developing an innovative concept of immunotherapy based on mesenchymal stromal cells DIABETER · Project Director Nadir Askenasy |
| 2015–2017 |
Genetically engineered apolipoproteins immobilized on nanoparticles: a Molecular Trojan horse targeting atherosclerotic plaque APGEN · PN-II-RU-TE-2014-4-2143, Projects for Young Research Teams, CNCSIS Romania · Project Director A. Gafencu |
| 2011–2016 |
Apolipoprotein E-based novel anti-atherosclerosis cell-therapy approaches PN-II ID_PCE-2011-3-0591, CNCSIS Romania · Project Director A. Gafencu |
| 2009–2011 |
Novel strategies employing genetic engineering to increase plasma HDL – the protective lipoproteins in atherosclerosis Exploratory research project 1307, CNCSIS Romania · Project Director A. Gafencu |
| 2005–2007 |
Regulation of apolipoprotein gene clusters – an innovative therapeutic approach of neurodegenerative and cardiovascular diseases Romanian Ministry of Research, Excellence Research Program: Projects for Young Researchers · Project Director A. Gafencu |
| 2005–2007 |
Regulation of the expression of the human apolipoprotein E gene in macrophages and the brain: new approaches for the treatment of dyslipidemias and Alzheimer’s disease Greek & Romanian Ministries of Research · Prof. Dimitris Kardassis & Dr. Anca Gafencu |
| 2003–2005 |
ApoE gene regulation – therapeutic target in cardiovascular and neurodegenerative diseases National Research Program for Biotechnology “BIOTECH” · Project Director A. Gafencu |
| 2001–2003 |
Characterization of albumin and IgG receptors, expressed by the endothelial cells in normal and pathologic states National Research Program “CERES” · Project Director A. Gafencu |
| 2000 |
Functional analysis of the IgG receptors in endothelial cells Romanian Research Ministry · Project Director A. Gafencu |
| 1999 |
Identification of FcR in human placental endothelial cells Romanian Academy · Project Director A. Gafencu |
| 1998 |
Immortalization of endothelial cells Romanian Academy · Project Director A. Gafencu |
| 1997–1998 |
Lipid composition of the microdomains of the endothelial cell membrane Romanian Academy · Project Director A. Gafencu |
| 1996–1999 |
Biochemical and functional characterization of the endothelial plasmalemma Romanian Research Ministry · Project Director A. Gafencu |
Gene regulation and molecular therapies